Facilitation of lordosis in the female rat by midbrain central gray infusions of substance P

Dornan, Wayne Allan (1984) Facilitation of lordosis in the female rat by midbrain central gray infusions of substance P. Masters thesis, Memorial University of Newfoundland.

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    Available under License - The author retains copyright ownership and moral rights in this thesis. Neither the thesis nor substantial extracts from it may be printed or otherwise reproduced without the author's permission.
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Abstract

Infusions of LHRH ( 50ng ), and Substance P ( 50ng, 500ng, and lug ) into the midbrain central gray led to a prompt facilitation of lordosis which was evident as early as 5 minutes post infusion, and depending on the dose had a duration of at least 120 minutes. Despite an apparent trend, different doses of substance P did not produce a signifcant dose-dependent facilitation of lordosis. Doses of substance P ( 50ng ), and LHRH ( 50ng ), produced effects on lordosis scores, but did not differ between tests. Administration of an anti-serum raised in rabbits against substance P failed to produce a statistically significant reduction in lordosis scores, although here too, a trend was evident.

Item Type: Thesis (Masters)
URI: http://research.library.mun.ca/id/eprint/5804
Item ID: 5804
Additional Information: Bibliography: leaves 84-95.
Department(s): Humanities and Social Sciences, Faculty of > Psychology
Science, Faculty of > Psychology
Date: 1984
Date Type: Submission
Library of Congress Subject Heading: Rats--Behavior; Substance P; Sexual behavior in animals

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