The influence of human core temperature on minute ventilation

Sancheti, Ajay (2002) The influence of human core temperature on minute ventilation. Masters thesis, Memorial University of Newfoundland.

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    Available under License - The author retains copyright ownership and moral rights in this thesis. Neither the thesis nor substantial extracts from it may be printed or otherwise reproduced without the author's permission.
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Abstract

Body temperature is known to affect human ventilation (Vg), yet the nature and mechanisms of this relationship are not resolved. The first study in this thesis explores how exercise-induced increases in body temperature affects ventilatory components, namely tidal volume (Vt) and frequency of respiration (f), and if these relationships are reproducible. Expressed as a function of esophageal temperature (Tes) in seven adult males during incremental exercise to maximum, ventilation and its components were reproducible using intraclass correlation coefficients, 0,84 < R < 0.93 (p<0.05). Since the relationships between ventilation variables and Tes were reproducible, a second study examined whether the mechanism of this effect could be mediated by an increased ventilatory sensitivity to C02- Central sensitivity to C02 was assessed using a modified Read rebreathing protocol before and after exercise induced warming in 6 male subjects. The slope and threshold point of ventilation expressed as a function of end tidal carbon dioxide were increased and decreased respectively, indicating an increased to sensitivity to C02 after body warming. In conclusion, the results support core temperature influence on human ventilation in a reproducible manner and that the effect of ventilation may be partially mediated by an increased central sensitivity to carbon dioxide.

Item Type: Thesis (Masters)
URI: http://research.library.mun.ca/id/eprint/1462
Item ID: 1462
Additional Information: Includes bibliographical references
Department(s): Human Kinetics and Recreation, School of
Date: 2002
Date Type: Submission
Library of Congress Subject Heading: Body temperature; Respiration

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