High level medium chain triglyceride feeding, energy expenditure and substrate oxidation in college-aged, non-obese women

Alexandrou, Elena (2004) High level medium chain triglyceride feeding, energy expenditure and substrate oxidation in college-aged, non-obese women. Masters thesis, Memorial University of Newfoundland.

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Abstract

This thesis assessed how short term feeding of high levels of dietary medium triglyceride (MCT) affected energy expenditure and postprandial substrate oxidation rates in females. Eight healthy, non-obese (BMI = 21.5 ± 0. 7 kg/m2), college aged (22.6 ± 0.5y) volunteers were fed both a MCT-rich and an isocaloric LCT-rich diet for two 1 week periods separated by 14 d. The energy content in each diet was 45% carbohydrates, 40% fat and 15% protein. The 2 diets had either 60.81% or 1.11% of total fat energy from MCT with the remaining fat energy intake from LCT. On days 1 and 7 of each diet, basal metabolic rate (BMR) and postprandial energy expenditure (PEE) were measured by indirect calorimetry with a ventilated hood. Results on days 1 and 7 showed no significant differences between diets for BMR or mean PEE. Fat oxidation for the MCT-rich diet was significantly greater (0.0001≤ p ≤ 0.04) than that for the LCT-rich diet at different time points across the 5.5 h postprandial period both on day 1 and 7 of feeding. It followed that postprandial carbohydrate oxidation rates on days 1 and 7 were significantly lower (0.0005 ≤ p ≤ 0.03) for the MCT-rich vs. the LCT-rich diet. In conclusion, relative to values for a LCT-rich diet, a MCT-rich diet gave a significantly increased postprandial fat oxidation rate but no effect on BMR or mean PEE. The results support that increasing proportions of MCT in the diet may help give a negative fat balance for women.

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