Active RAS/MEK pathway downregulates expression of IFN-inducible genes by targeting IRF1: implications for understanding molecular mechanisms of viral oncolysis

Komatsu, Yumiko (2016) Active RAS/MEK pathway downregulates expression of IFN-inducible genes by targeting IRF1: implications for understanding molecular mechanisms of viral oncolysis. Doctoral (PhD) thesis, Memorial University of Newfoundland.

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Item Type: Thesis (Doctoral (PhD))
URI: http://research.library.mun.ca/id/eprint/12217
Item ID: 12217
Additional Information: Includes bibliographical references (pages 134-175). -- Restricted until 12/31/2018.
Keywords: viral oncolysis, IRF1, Ras/MEK
Department(s): Medicine, Faculty of > Biomedical Sciences
Date: May 2016
Date Type: Submission
Library of Congress Subject Heading: Cancer--Gene therapy; Interferon; Antioncogenes; Tumor suppressor proteins

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