Omega-3 fatty acid supplementation in the treat of attention deficit/hyperactivity disorder: a pilot study

Bonnell, Weldon Scot (2013) Omega-3 fatty acid supplementation in the treat of attention deficit/hyperactivity disorder: a pilot study. Masters thesis, Memorial University of Newfoundland.

[img] [English] PDF - Accepted Version
Available under License - The author retains copyright ownership and moral rights in this thesis. Neither the thesis nor substantial extracts from it may be printed or otherwise reproduced without the author's permission.

Download (29Mb)

Abstract

Background and Purpose: Omega-3 fatty acids are essential for brain development but their dietary intake is low. Controlled trials of omega-3 fatty acids in Attention deficit/hyperactivity disorder (ADHD) suggest benefit but have limitations. The purpose was to conduct a small clinical trial to serve as a pilot study. -- Methods: This was a randomized, double blind, placebo controlled trial, supplementing youth (6-17 years old) with ADHD, with an omega-3 fatty acid supplement or identical placebo for 6 months. The primary outcome measure was the Conners' ADHD scale. -- Results: There were recruitment problems requiring inclusion/exclusion criteria revision. Seven (of 10) patients per group were recruited. Withdrawal was a problem; 57% of participants did not return following treatment assignment. One participant per group completed the study. Treatment assignment did not affect study withdrawal. Tolerability was a major reason for withdrawal in both groups. No differences in study outcomes were detected. -- Conclusions: Several limitations and potential protocol enhancements were identified, including a change of supplement. No conclusions could be made regarding the efficacy of this supplement in the treatment of ADHD.

Item Type: Thesis (Masters)
URI: http://research.library.mun.ca/id/eprint/10178
Item ID: 10178
Additional Information: Includes bibliographical references (leaves 100-104).
Department(s): Medicine, Faculty of
Date: 2013
Date Type: Submission
Library of Congress Subject Heading: Attention-deficit hyperactivity disorder--Diet therapy; Attention-deficit-disordered youth; Omega-3 fatty acids; Dietary supplements
Medical Subject Heading: Attention Deficit Disorder with Hyperactivity--diet therapy; Adolescent; Fatty Acids, Omega-3--therapeutic use; Dietary Supplements

Actions (login required)

View Item View Item

Downloads

Downloads per month over the past year

View more statistics